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    tmem62 transmembrane protein 62 [ Danio rerio (zebrafish) ]

    Gene ID: 402997, updated on 27-Mar-2024

    Summary

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    Official Symbol
    tmem62provided by ZNC
    Official Full Name
    transmembrane protein 62provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1837
    See related
    Ensembl:ENSDARG00000053890 AllianceGenome:ZFIN:ZDB-GENE-040426-1837
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:77419
    Summary
    Predicted to enable hydrolase activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in female organism. Orthologous to human TMEM62 (transmembrane protein 62). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 17
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (37253600..37281320)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (37306011..37334145)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 30 member 1b Neighboring gene hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b Neighboring gene prostaglandin reductase 2 Neighboring gene mitotic deacetylase associated SANT domain protein b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Brain transcriptome analysis of a familial Alzheimer's disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production. Newman M, et al. Mol Brain, 2019 May 3. PMID 31053140, Free PMC Article
    2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC77419

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 62

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      37253600..37281320
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001923726.6 → XP_001923761.1  transmembrane protein 62

      UniProtKB/TrEMBL
      A0A8M1QRB9, E7FFQ5
      Related
      ENSDARP00000070483.5, ENSDART00000076004.7
      Conserved Domains (3) summary
      cd07401
      Location:58 → 346
      MPP_TMEM62_N; Homo sapiens TMEM62, N-terminal metallophosphatase domain
      pfam00149
      Location:57 → 260
      Metallophos; Calcineurin-like phosphoesterase
      cl00199
      Location:289 → 401
      SO_family_Moco; Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the ...

    RNA

    1. XR_002455960.1 RNA Sequence

      Related
      ENSDART00000134000.2

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_205696.1: Suppressed sequence

      Description
      NM_205696.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein Strain
    Heading Accession and Version

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